Search Ontology:
ChEBI
onalespib
- Term ID
- CHEBI:140592
- Synonyms
-
- (2,4-dihydroxy-5-isopropylphenyl)-(5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl)methanone
- (2,4-dihydroxy-5-isopropylphenyl){5-[(4-methylpiperazin-1-yl)methyl]-1,3-dihydro-2H-isoindol-2-yl}methanone
- AT 13387
- AT-13387
- AT13387
- onalespib
- onalespibum
- Definition
- A member of the class of isoindoles that is isoindole in which the amino group has been acylated by a 2,4-dihydroxy-5-isopropylbenzoyl group and in which position 5 of the isoidole moiety has been substituted by a (4-methylpiperazin-1-yl)methyl group. A second-generation Hsp90 inhibitor.
- References
-
- CAS:912999-49-6
- DrugBank:DB06306
- KEGG:D10719
- PDBeChem:XJX
- PMCID:PMC4638428
- PMID:20662534
- PMID:21538821
- PMID:22181674
- PMID:22714264
- PMID:23186098
- PMID:24156782
- PMID:25336693
- PMID:25349308
- PMID:26082332
- PMID:26248657
- PMID:26452257
- PMID:26627081
- PMID:27156227
- PMID:27197266
- PMID:27321499
- PMID:27673365
- PMID:28679777
- PMID:31638190
- Reaxys:18536397
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from onalespib
Phenotype where environments contain onalespib
Phenotype modified by environments containing onalespib
Human Disease Model