Search Ontology:
ChEBI

ANA-12

Term ID
CHEBI:140465
Synonyms
  • ANA12
  • N-{2-[(2-oxoazepan-3-yl)carbamoyl]phenyl}-1-benzothiophene-2-carboxamide
  • TrkB antagonist
Definition
A secondary carboxamide that is anthranilic acid in which the carboxy group has undergone condensation with the primary amino group of alpha-amino-epsilon-caprolactam, while the aryl-amino group has undergone condensation with the carboxy group of 1-benzothiophene-2-carboxylic acid. It is a selective, non-competitive antagonist of tropomyosin receptor kinase B (TrkB, also known as tyrosine receptor kinase B).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from ANA-12
Phenotype where environments contain ANA-12
Phenotype modified by environments containing ANA-12
Human Disease / Model Data