Search Ontology:
ChEBI
cefiderocol
- Term ID
- CHEBI:140376
- Synonyms
-
- (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-({1-[2-(2-chloro-3,4-dihydroxybenzamido)ethyl]pyrrolidinium-1-yl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- cefiderocol
- cefiderocolum
- GSK 2696266
- GSK-2696266
- GSK2696266
- RSC 649266
- S 649266
- S-649266
- S649266
- Definition
- A fourth-generation siderophore cephalosporin antibiotic having {1-[2-(2-chloro-3,4-dihydroxybenzamido)ethyl]pyrrolidinium-1-yl}methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino side groups located at positions 3 and 7 respectively, developed to combat a variety of bacterial pathogens, including beta-lactam- and carbapenem-resistant organisms.
- References
-
- CAS:1225208-94-5
- Chemspider:52084902
- DrugBank:DB14879
- Drug_Central:5352
- KEGG:D11302
- PMCID:PMC6253113
- PMCID:PMC7776597
- PMCID:PMC7777002
- PMID:27139465
- PMID:28369471
- PMID:28748397
- PMID:28848004
- PMID:29017833
- PMID:29061741
- PMID:29111435
- PMID:29311072
- PMID:29318906
- PMID:29471305
- PMID:29960205
- PMID:30323050
- PMID:30730562
- PMID:32522005
- PMID:32727829
- PMID:33068441
- PMID:33164837
- PMID:33199383
- PMID:33313656
- PMID:33393598
- PMID:33532823
- PMID:33573148
- PMID:33670891
- PMID:33677539
- PMID:33849355
- PMID:33894839
- PMID:33915286
- Patent:EP2341053
- Reaxys:21605074
- Wikipedia:Cefiderocol
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from cefiderocol
Phenotype where environments contain cefiderocol
Phenotype modified by environments containing cefiderocol
Human Disease Model