cyclosporin A metabolite M18

Term ID

CHEBI:140175

Synonyms

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(2R,3R)-5-(2-hydroxyethyl)-3-methyltetrahydrofuran-2-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14
AM1c
cyclosporin A metabolite AM1c
cyclosporin metabolite AM1c
cyclosporin metabolite M18
cyclosporine A metabolite AM1c
cyclosporine A metabolite M18
cyclosporine metabolite AM1c
cyclosporine metabolite M18
M18

Definition

A cyclosporin A derivative that is cyclosporin A metabolite M17 in which the hydroxy group at position 3 of residue 1 [(2S,3R,4R,6E)-3,8-dihydroxy-4-methyl-2-(methylamino)oct-6-enamide] has undergone addition to the double bond at position 6 to afford the corresponding dioxolane ring.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclosporin A derivative oxolanes

cyclosporin A derivative oxolanes Show first 5 Terms
has_functional_parent: cyclosporin A metabolite M17

cyclosporin A metabolite M17 Show first 5 Terms
has_role: drug metabolite

drug metabolite Show first 5 Terms
inverse has_functional_parent: cyclosporin A metabolite M1cAL

cyclosporin A metabolite M1cAL Show first 5 Terms

Phenotype

Phenotype resulting from cyclosporin A metabolite M18

Phenotype where environments contain cyclosporin A metabolite M18

Phenotype modified by environments containing cyclosporin A metabolite M18

Human Disease Model