cyclosporin A metabolite M25

Term ID

CHEBI:140172

Synonyms

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1,6-dihydroxy-2-methylhex-4-en-1-yl]-30-ethyl-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26
AM14N
cyclosporin A metabolite AM14N
cyclosporin metabolite AM14N
cyclosporin metabolite M25
cyclosporine A metabolite AM14N
cyclosporine A metabolite M25
cyclosporine metabolite AM14N
cyclosporine metabolite M25
M25

Definition

A cyclosporin A derivative that is cyclosporin A in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has undergone allylic oxidation to give the corresponding primary allylic alcohol, while residue 4, N-methylleucine, has undergone N-demethylation.

References

PMID:2642763

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclosporin A derivative primary allylic alcohol

cyclosporin A derivative primary allylic alcohol Show first 5 Terms
has_functional_parent: cyclosporin A metabolite M17 cyclosporin A metabolite M21

cyclosporin A metabolite M17 cyclosporin A metabolite M21 Show first 5 Terms
has_role: drug metabolite

drug metabolite Show first 5 Terms

Phenotype

Phenotype resulting from cyclosporin A metabolite M25

Phenotype where environments contain cyclosporin A metabolite M25

Phenotype modified by environments containing cyclosporin A metabolite M25

Human Disease Model