cyclosporin A metabolite M8

Term ID

CHEBI:140158

Synonyms

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1,6-dihydroxy-2-methylhex-4-en-1-yl]-30-ethyl-9-(2-hydroxy-2-methylpropyl)-6,18,24-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacon
AM19
cyclosporin A metabolite AM19
cyclosporin metabolite AM19
cyclosporin metabolite M8
M8

Definition

A cyclosporin A derivative that is cyclosporin A in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has undergone allylic oxidation to give the corresponding primary allylic alcohol, and in which residue 9 (N-methylleucine) has undergone oxidation so as to introduce a hydroxy group at the carbon bearing the two methyl groups.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclosporin A derivative primary allylic alcohol tertiary alcohol

cyclosporin A derivative primary allylic alcohol tertiary alcohol Show first 5 Terms
has_functional_parent: cyclosporin A metabolite M1 cyclosporin A metabolite M17

cyclosporin A metabolite M1 cyclosporin A metabolite M17 Show first 5 Terms
has_role: drug metabolite

drug metabolite Show first 5 Terms
inverse has_functional_parent: cyclosporin A metabolite M26

cyclosporin A metabolite M26 Show first 5 Terms

Phenotype

Phenotype resulting from cyclosporin A metabolite M8

Phenotype where environments contain cyclosporin A metabolite M8

Phenotype modified by environments containing cyclosporin A metabolite M8

Human Disease Model