Search Ontology:
ChEBI

cyclosporin A metabolite M8

Term ID
CHEBI:140158
Synonyms
  • (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1,6-dihydroxy-2-methylhex-4-en-1-yl]-30-ethyl-9-(2-hydroxy-2-methylpropyl)-6,18,24-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacon
  • AM19
  • cyclosporin A metabolite AM19
  • cyclosporin metabolite AM19
  • cyclosporin metabolite M8
  • M8
Definition
A cyclosporin A derivative that is cyclosporin A in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has undergone allylic oxidation to give the corresponding primary allylic alcohol, and in which residue 9 (N-methylleucine) has undergone oxidation so as to introduce a hydroxy group at the carbon bearing the two methyl groups.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from cyclosporin A metabolite M8
Phenotype where environments contain cyclosporin A metabolite M8
Phenotype modified by environments containing cyclosporin A metabolite M8
Human Disease / Model Data