Search Ontology:
ChEBI
sepantronium bromide
- Term ID
- CHEBI:139608
- Synonyms
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- 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide
- 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide
- bromure de sepantronium
- bromuro de sepantronio
- sepantronii bromidum
- sepantronium bromide
- YM 155
- YM-155
- Definition
- An organic bromide salt consisting of sepantronium cations and bromide anions. It has been found to selectively inhibit survivin (BIRC5) gene promoter activity and to down-regulate survivin in vitro, so leading to induction of apoptosis.
- References
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- CAS:781661-94-7
- KEGG:D10164
- PMID:22787117
- PMID:22806304
- PMID:22842455
- PMID:22892872
- PMID:23138529
- PMID:23325792
- PMID:23740602
- PMID:23857959
- PMID:24297644
- PMID:24432379
- PMID:24518133
- PMID:24993306
- PMID:25033765
- PMID:25296978
- PMID:25533314
- PMID:25659731
- PMID:25955434
- PMID:26023798
- PMID:26090615
- PMID:26547260
- PMID:26857688
- PMID:27151995
- PMID:27271121
- PMID:27754993
- PMID:28618939
- Patent:EP2127652
- Patent:US7618992
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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Phenotype
Phenotype resulting from sepantronium bromide
Phenotype where environments contain sepantronium bromide
Phenotype modified by environments containing sepantronium bromide
Human Disease / Model Data