piericidin A

Term ID

CHEBI:138511

Synonyms

(+)-piericidin A1
2-[(2E,5E,7E,11E)-10R-hydroxy-3,7,9R,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-5,6-dimethoxy-3-methyl-4-pyridinol
2-[(2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-5,6-dimethoxy-3-methylpyridin-4-ol
2-[(2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraenyl]-5,6-dimethoxy-3-methyl-1H-pyridin-4-one
AR 054
Piericidin A1
Shaoguanmycin B
SN 198E

Definition

A member of the class of monohydroxypyridines that acts as an irreversible mitochondrial Complex I inhibitor that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of NADH:ubiquinone oxidoreductase

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether methylpyridines monohydroxypyridine secondary allylic alcohol

aromatic ether methylpyridines monohydroxypyridine secondary allylic alcohol Show first 5 Terms
has_role: antimicrobial agent bacterial metabolite EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor mitochondrial respiratory-chain inhibitor

antimicrobial agent bacterial metabolite EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor mitochondrial respiratory-chain inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from piericidin A

Phenotype where environments contain piericidin A

Phenotype modified by environments containing piericidin A

Human Disease / Model Data