sofalcone

Term ID

CHEBI:135732

Synonyms

• 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]-acetic acid
• Lavin
• sofalcona
• sofalcone
• sofalconum
• Solon
• SU-88
• Tofalcone
• {5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy}acetic acid

Definition

A member of the class of chalcones that is benzene in which the hydrogens at positions 1,2 and 5 are replaced by carboxymethoxy, (1E)-1-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}-3-oxoprop-1-en-3-yl, and (3-methylbut-2-en-1-yl)oxy groups, respectively. It is a gastrointestinal drug currently used for treatment of gastritis and gastric ulcers in Japan and South Korea.

References

• CAS:153175-87-2
• CAS:64506-49-6
• DrugBank:DB05197
• Drug_Central:2456
• HMDB:HMDB0042013
• KEGG:D01956
• PMID:11979875
• PMID:15786539
• PMID:17586104
• PMID:19239904
• PMID:20586860
• PMID:20599750
• PMID:21530127
• PMID:25667213
• PMID:31386809
• PMID:31614142
• PMID:7084818
• PMID:7735929
• PMID:7835618
• PMID:8959521
• Patent:CN1733682
• Reaxys:2191482
• Wikipedia:Sofalcone

Ontology

ChEBI  ( EBI )

Resources

CTD