Search Ontology:
ChEBI

taltirelin

Term ID
CHEBI:135653
Synonyms
  • 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide
  • N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide
  • TA 0910
  • TA-0910
  • taltirelin
  • taltirelin hydrate
  • taltirelina
  • taltireline
  • taltirelinum
Definition
An oligopeptide comprising of (4S)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid, L-histidine and L-prolinamide joined in sequence by peptide linkages. It is a thyrotropin-releasing hormone (TRH) analog. Its tetrahydrate form is approved in Japan for the treatment of spinal muscular atrophy.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
inverse has_part
Phenotype
Phenotype resulting from taltirelin
Phenotype where environments contain taltirelin
Phenotype modified by environments containing taltirelin
Human Disease Model
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