Search Ontology:
ChEBI
neticonazole
- Term ID
- CHEBI:135281
- Synonyms
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- 1-{(E)-2-(methylthio)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole
- Atolant
- neticonazol
- neticonazole
- neticonazolum
- Definition
- An enamine that is ethene which is substituted at positions 1, 1, and 2 by o-pentoxyphenyl, 1H-imidazol-1-yl, and methylthio groups, respectively (the E isomer). An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan (generally as the corresponding hydrochloride salt) as an antifungal drug for the treatment of superficial skin infections.
- References
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- CAS:130726-68-0
- Drug_Central:1902
- PMID:11156023
- PMID:16651719
- PMID:8254891
- PMID:8734665
- PMID:9062749
- Patent:CA2458026
- Patent:EP1568366
- Patent:EP227011
- Patent:US4740601
- Reaxys:5381743
- Wikipedia:Neticonazole
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
- has_role
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- inverse is_conjugate_acid_of
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- is_conjugate_base_of
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Phenotype
Phenotype resulting from neticonazole
Phenotype where environments contain neticonazole
Phenotype modified by environments containing neticonazole
Human Disease / Model Data