alpha-D-GlcpNAc-(1->3)-[P-6-[CH2]5NH2]-alpha-D-GlcpNAc-(1->2)-D-GroA

Term ID

CHEBI:134200

Synonyms

• (2R)-2-{[2-acetamido-3-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-6-O-{[(5-aminopentyl)oxy](hydroxy)phosphoryl}-2-deoxy-alpha-D-glucopyranosyl]oxy}-3-hydroxypropanoic acid
• (2R)-2-{[N-acetyl-alpha-D-glucosaminyl-(1->3)-N-acetyl-6-O-(5-aminopentylphospho)-alpha-D-glucosaminyl]oxy}-3-hydroxypropionic acid
• 2-N-acetyl-alpha-D-glucosaminopyranosyl-(1->3)-2-N-acetyl-6-(5-aminopentylphosphoryl)-alpha-D-glucosaminopyranosyl-(1->2)-(2R)-3-hydroxypropanoic acid
• alpha-D-GlcpNAc-(1->3)-alpha-D-GlcpNAc6(P-[CH2]5NH2)-(1->2)-D-GroA

Definition

A synthetic disaccharide phosphate consisting of an alpha-D-GlcNAc-(1->3)-alpha-D-GlcNAc disaccharide linked glycosidically to O-2 of D-glyceric acid and connected to a 5-aminopentyl linker via a phospho group at O-6 of the reducing-end residue. Synthesized for immobilization on microarray surfaces and conjugation to carrier proteins as a potential vaccine candidate to protect from Clostridium difficile infections.

References

• PMID:23836132
• PMID:27524293
• Reaxys:23876125

Ontology

ChEBI  ( EBI )