yanuthone X2

Term ID

CHEBI:133037

Synonyms

(1R,5S,6R)-5-hydroxy-4-methoxy-1-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
yanuthone X2
yanuthone-X2

Definition

A class II yanuthone that is 5,6-epoxy-cyclohex-2-en-1-one which is substituted at positions 3, 4, and 6 by methoxy, hydroxy, and trans,trans-farnesyl groups, respectively (the 4S,5R,6R stereoisomer). Isolated from the filamentous fungus Aspergillus niger, it shows antifungal activity towards the pathogenic yeast Candida albicans (IC50 = 51.7 +-4.7 muM).

References

PMID:25293978

Ontology

ChEBI ( EBI )

Relationships

is a type of: class II yanuthone enol ether secondary alcohol

class II yanuthone enol ether secondary alcohol Show first 5 Terms
has_functional_parent: (2-trans,6-trans)-farnesol

(2-trans,6-trans)-farnesol Show first 5 Terms
has_role: antifungal agent Aspergillus metabolite

antifungal agent Aspergillus metabolite Show first 5 Terms
inverse has_functional_parent: yanuthone X1

yanuthone X1 Show first 5 Terms

Phenotype

Phenotype resulting from yanuthone X2

Phenotype where environments contain yanuthone X2

Phenotype modified by environments containing yanuthone X2

Human Disease Model