cyclomorusin A

Term ID

CHEBI:132868

Synonyms

6,11-dihydroxy-3,3-dimethyl-8-(2-methylprop-1-en-1-yl)-3H,7H,8H-chromeno[4,3-b]pyrano[2,3-h]chromen-7-one
cyclomorusin

Definition

An extended flavonoid that is cyclomulberrin in which the hydroxy group at position 10 has undergone oxidative cyclisation to position 3 of the 3-methylbut-2-en-1-yl substituent, with migration of the double bond into conjugation with the aromatic ring. It is a moderate inhibitor of acetylcholinesterase (IC50 = 16.2 - 36.6 muM), and a strong inhibitor of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) induced platelet aggregation.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclic ketone extended flavonoid organic heteropentacyclic compound polyphenol

cyclic ketone extended flavonoid organic heteropentacyclic compound polyphenol Show first 5 Terms
has_functional_parent: cyclomulberrin

cyclomulberrin Show first 5 Terms
has_role: EC 1.14.18.1 (tyrosinase) inhibitor EC 3.1.1.7 (acetylcholinesterase) inhibitor plant metabolite platelet aggregation inhibitor

EC 1.14.18.1 (tyrosinase) inhibitor EC 3.1.1.7 (acetylcholinesterase) inhibitor plant metabolite platelet aggregation inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from cyclomorusin A

Phenotype where environments contain cyclomorusin A

Phenotype modified by environments containing cyclomorusin A

Human Disease / Model Data