Search Ontology:
ChEBI

salubrinal

Term ID
CHEBI:131923
Synonyms
  • (2E)-3-phenyl-N-{2,2,2-trichloro-1-[(quinolin-8-ylcarbamothioyl)amino]ethyl}acrylamide
  • (E)-3-phenyl-N-[2,2,2-trichloro-1-(quinolin-8-ylcarbamothioylamino)ethyl]prop-2-enamide
Definition
A member of the class of quinolines that is a mixed aminal resulting from the formal condensation oftrichloroacetaldehyde with the amide nitrogen of trans-cinnamamide and the primary amino group of 1-quinolin-8-ylthiourea. It is a selective inhibitor of cellular complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha).
References
(all 30)
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
Phenotype
Phenotype resulting from salubrinal
Phenotype where environments contain salubrinal
Phenotype modified by environments containing salubrinal
Human Disease Model
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