CFTRinh-172

Term ID

CHEBI:131686

Synonyms

(inh)-172
3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone
4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid
5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone
C2992_SIGMA
CFTR(inh)-172
Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172
cystic fibrosis transmembrane regulator inhibitor 172

Definition

A thiazolidinone that is 2-thioxo-4-thiazolidinone which is substituted at position 3 by a (m--trifluoromethyl)phenyl group and at position 5 by a p-carboxybenzylidene group. It is an inhibitor of cystic fibrosis transmembrane conductance regulator, a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: (trifluoromethyl)benzenes benzoic acids thiazolidinone

(trifluoromethyl)benzenes benzoic acids thiazolidinone Show first 5 Terms
has_role: EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor

EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from CFTRinh-172

Phenotype where environments contain CFTRinh-172

Phenotype modified by environments containing CFTRinh-172

Human Disease / Model Data