Search Ontology:
ChEBI
phosphonoformic acid
- Term ID
- CHEBI:127780
- Synonyms
-
- carboxyphosphonic acid
- dihydroxyphosphanecarboxylic acid oxide
- Foscarmet
- Definition
- Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
- References
-
- CAS:4428-95-9
- DrugBank:DB00529
- Drug_Central:1241
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_functional_parent
-
- has_role
-
- inverse has_functional_parent
-
- inverse is_conjugate_base_of
-
- is_conjugate_acid_of
-
Show first 5 Terms
Phenotype
Phenotype resulting from phosphonoformic acid
No data available
Phenotype where environments contain phosphonoformic acid
| Fish | Conditions | Phenotype | Term | Figures |
|---|---|---|---|---|
| uhrf1hi272Tg/hi272Tg; gl23Tg | chemical treatment: phosphonoformic acid | Fig. 6  from Chernyavskaya et al., 2017 |
1 - 1 of 1
Show
Phenotype modified by environments containing phosphonoformic acid
| Fish | Modification | Conditions | Phenotype | Term | Figures |
|---|---|---|---|---|---|
| uhrf1hi272Tg/hi272Tg; gl23Tg | ameliorated | chemical treatment: phosphonoformic acid | Fig. 6 from Chernyavskaya et al., 2017 |
1 - 1 of 1
Show
Human Disease Model