Search Ontology:
ChEBI

cinalukast

Term ID
CHEBI:126598
Synonyms
  • 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid
  • 4-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}amino)-2,2-diethyl-4-oxobutanoic acid
  • cinalukast
Definition
2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in the human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.
References
  • CAS:128312-51-6
  • DrugBank:DB00587
  • Drug_Central:648
  • KEGG:D02846
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from cinalukast
Phenotype where environments contain cinalukast
Phenotype modified by environments containing cinalukast
Human Disease / Model Data