| Term: | Mauthner neuron AMPA glutamate receptor complex |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | Mauthner neuron |
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| Synonyms: | |
| Definition: | Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon. |
| Ontology: | Anatomy Ontology [ZFA:0009149] |
| Name: | AMPA glutamate receptor complex |
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| Synonyms: | alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, AMPA receptor, AMPA-selective glutamate receptor complex |
| Definition: | An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. |
| Ontology: | GO: Cellular Component [GO:0032281] QuickGO AmiGO |