| Term: | skeletal muscle dystroglycan complex |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | skeletal muscle |
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| Synonyms: | |
| Definition: | Muscle, composed of long cylindrical, multinucleated cells that attaches to the skeleton via tendons. |
| Ontology: | Anatomy Ontology [ZFA:0005277] |
| Name: | dystroglycan complex |
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| Synonyms: | |
| Definition: | A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin. |
| Ontology: | GO: Cellular Component [GO:0016011] QuickGO AmiGO |