| Term: | macula saccule cell death |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | macula saccule |
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| Synonyms: | saccular macula |
| Definition: | Portion of tissue that is a patch of thickened, pseudostratified epithelium in the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. The macula saccule senses linear acceleration and gravity. In juveniles the macula saccule is oriented vertically in a plane running along the anterioposterior body axis. It covers the medial wall of the saccule along most of its length. |
| Ontology: | Anatomy Ontology [ZFA:0007000] |
| Name: | cell death |
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| Synonyms: | accidental cell death, necrosis |
| Definition: | Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). |
| Ontology: | GO: Biological Process [GO:0008219] QuickGO AmiGO |