| Term: | hematopoietic multipotent progenitor cell DNA repair |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | hematopoietic multipotent progenitor cell |
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| Synonyms: | hemopoietic progenitor cell |
| Definition: | A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. |
| Ontology: | Anatomy Ontology [ZFA:0009354] |
| Name: | DNA repair |
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| Synonyms: | |
| Definition: | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| Ontology: | GO: Biological Process [GO:0006281] QuickGO AmiGO |