Term: | otic vesicle epithelial to mesenchymal transition |
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Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | otic vesicle |
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Synonyms: | otic capsule, otocyst, ov |
Definition: | Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells. (Also see Anatomical Atlas entry for ear by T. Whitfield.) |
Ontology: | Anatomy Ontology [ZFA:0000051] |
Name: | epithelial to mesenchymal transition |
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Synonyms: | EMT, epithelial-mesenchymal transition, mesenchymal cell differentiation from epithelial cell |
Definition: | A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. |
Ontology: | GO: Biological Process [GO:0001837] QuickGO AmiGO |