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Phenotype Figure Summary
Marker:
klf4
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Chen
et al.
, 2019
Fig 2
klf4
as32/+
, 
klf4
as32/as32
epidermis somatic stem cell decreased amount, abnormal
ionocyte decreased amount, abnormal
keratinocyte decreased amount, abnormal
Fig 3
WT + MO1-klf4 + MO2-klf4
ionocyte decreased amount, abnormal
Fig 4
WT + MO1-klf4 + MO2-klf4
extension NaK ionocyte decreased amount, abnormal
extension vH ionocyte decreased amount, abnormal
Fig 5
WT + MO1-klf4 + MO2-klf4 + MO4-tp53
, 
WT + MO1-klf4 + MO2-klf4
ectoderm cell population proliferation occurrence, ameliorated
ectoderm stem cell proliferation decreased occurrence, abnormal
Fig. S1
WT + MO1-klf4 + MO2-klf4
epidermis somatic stem cell decreased amount, abnormal
ionocyte decreased amount, abnormal
keratinocyte decreased amount, abnormal
Fig. S13
WT + MO1-klf4 + MO2-klf4 + MO4-tp53
, 
WT + MO1-klf4 + MO2-klf4
ionocyte decreased amount, abnormal
Fig. S2
klf4
as32/as32
ionocyte decreased amount, abnormal
Fig. S3
WT + MO1-klf4 + MO2-klf4
keratinocyte decreased amount, abnormal
Fig. S4
WT + MO1-klf4 + MO2-klf4
ionocyte decreased amount, abnormal
keratinocyte decreased amount, abnormal
Fig. S5
WT + MO1-klf4 + MO2-klf4
ball NaK ionocyte decreased amount, abnormal
ball vH ionocyte decreased amount, abnormal
Fig. S6
klf4
as32/+
epidermis somatic stem cell decreased amount, abnormal
Li
et al.
, 2011
Fig. 2
AB + MO2-klf4
, 
AB + MO1-klf4 + MO2-klf4
eye decreased size, abnormal
intestine distended, abnormal
intestine hypoplastic, abnormal
liver hypoplastic, abnormal
otic vesicle decreased size, abnormal
swim bladder non-functional, abnormal
tectal ventricle increased size, abnormal
whole organism dorsal-ventral axis decreased length, abnormal
Fig. 4
AB + MO1-klf4 + MO2-klf4
goblet cell decreased amount, abnormal
Fig. 5
AB + MO1-klf4 + MO2-klf4
enteroendocrine cell differentiation disrupted, abnormal
Fig. 6
AB + MO1-klf4 + MO2-klf4
goblet cell poorly differentiated, abnormal
intestinal bulb goblet cell decreased amount, abnormal
mid intestine goblet cell decreased amount, abnormal
posterior intestine goblet cell decreased amount, abnormal
Fig. 7
AB + MO1-klf4 + MO2-klf4
cell population proliferation increased rate, abnormal
Fig. S4
AB + MO1-klf4
eye decreased size, abnormal
intestine distended, abnormal
otic vesicle decreased size, abnormal
swim bladder non-functional, abnormal
tectal ventricle increased size, abnormal
whole organism dorsal-ventral axis decreased length, abnormal
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