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Phenotype Figure Summary
Marker:
cog4
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Clément
et al.
, 2018
Fig. 1
cog4
b1312/b1312
inner ear decreased size, abnormal
pillar of the semicircular canal malformed, abnormal
semicircular canal aplastic/hypoplastic, abnormal
Fig. 3
cog4
b1312/b1312
inner ear lacks parts or has fewer parts of type semicircular canal, abnormal
otic vesicle lacks parts or has fewer parts of type otic vesicle protrusion, abnormal
pillar of the semicircular canal malformed, abnormal
semicircular canal formation delayed, abnormal
Fig. 5
cog4
b1312/b1312
extracellular matrix organization disrupted, abnormal
otic vesicle protrusion proteoglycan decreased amount, abnormal
Fig. 6
cog4
b1312/b1312
extracellular matrix organization disrupted, abnormal
otic vesicle protrusion Collagen decreased amount, abnormal
Fig. S3
cog4
b1312/b1312
inner ear morphology, abnormal
Fig. S4
cog4
b1312/b1312
extracellular matrix organization disrupted, abnormal
otic vesicle protrusion proteoglycan decreased amount, abnormal
Fig. S5
cog4
b1312/b1312
otic vesicle ventral protrusion present, abnormal
pillar of the lateral semicircular canal absent, abnormal
pillar of the semicircular canal malformed, abnormal
semicircular canal Collagen present, abnormal
semicircular canal formation delayed, abnormal
Ferreira
et al.
, 2018
Fig. 6
cog4
b1312/b1312
, 
cog4
b1311/b1311
hair cell anterior macula stereocilium bundle decreased amount, abnormal
inner ear malformed, abnormal
neuromast hair cell stereocilium bundle decreased amount, abnormal
semicircular canal shape, abnormal
Fig. 7
cog4
b1311/+
; cog4
b1312/+
ceratohyal cartilage chondrocyte disorganized, abnormal
ceratohyal cartilage chondrocyte morphology, abnormal
eye decreased size, abnormal
inner ear decreased size, abnormal
mandibular arch skeleton decreased size, abnormal
pectoral fin
col1a2
expression decreased amount, abnormal
pectoral fin clavate, abnormal
pectoral fin decreased length, abnormal
whole organism decreased length, abnormal
Fig. S11
cog4
b1312/b1312
anterior macula Golgi apparatus structure, abnormal
Fig. S12
cog4
b1312/b1312
, 
cog4
b1311/b1311
protein N-linked glycosylation process quality, abnormal
protein O-linked glycosylation process quality, abnormal
whole organism glycosphingolipid decreased amount, abnormal
Fig. S14
cog4
b1312/b1312
; vu234Tg
hair cell anterior macula
cog4
expression decreased amount, abnormal
text only
cog4
b1312/b1312
, 
cog4
b1311/b1311
auditory behavior decreased occurrence, abnormal
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