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Phenotype Figure Summary
Marker:
slc35b2
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Wiweger
et al.
, 2012
Fig. 3
slc35b2
to14mx/to14mx
ossification delayed, abnormal
tooth mineralization delayed, abnormal
Fig. 4
slc35b2
to14mx/to14mx
ceratobranchial 5 bone decreased length, abnormal
ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
ossification delayed, abnormal
tooth mineralization delayed, abnormal
de Andrea
et al.
, 2011
Fig. 3
slc35b2
to216z/to216z
cranial cartilage extracellular matrix composition, abnormal
cranial cartilage poly(ethylene imine) spatial pattern, abnormal
Wiweger
et al.
, 2011
Fig. 1
slc35b2
to216z/to216z
glycosaminoglycan metabolic process disrupted, abnormal
Fig. 3
slc35b2
to216z/to216z
ceratohyal cartilage chondrocyte disorganized, abnormal
chondrocyte circular, abnormal
chondrocyte intercalation involved in growth plate cartilage morphogenesis arrested, abnormal
cranial cartilage extracellular matrix composition, abnormal
perichondrium cell increased size, abnormal
perichondrium increased thickness, abnormal
perichondrium rough, abnormal
Fig. 4
slc35b2
to216z/to216z
cranial cartilage collagen type I trimer decreased amount, abnormal
cranial cartilage collagen type VI trimer absent, abnormal
Fig. 5
slc35b2
to216z/to216z
cell junction organization disrupted, abnormal
chondrocyte attached to chondrocyte, abnormal
chondrocyte color, abnormal
chondrocyte plasma membrane undulate, abnormal
cranial cartilage collagen trimer morphology, abnormal
Fig. Table 2
slc35b2
to216z/to216z
chondrocyte nucleus shape, abnormal
cranial cartilage apoptotic, abnormal
cranial cartilage deformed, abnormal
ossification decreased occurrence, abnormal
perichondrium increased thickness, abnormal
whole organism anterior-posterior axis dwarf-like, abnormal
text only
slc35b2
to216z/to216z
ceratobranchial 5 bone ossified, abnormal
cleithrum decreased size, abnormal
cleithrum malformed, abnormal
dermal bone hypoplastic, abnormal
opercle decreased size, abnormal
opercle malformed, abnormal
Clément
et al.
, 2008
Fig. 1
slc35b2
to14mx/to14mx
cartilage development disrupted, abnormal
cartilage element decreased length, abnormal
cartilage element increased thickness, abnormal
chondrocyte morphology, abnormal
Fig. 5
slc35b2
to14mx/to14mx
skeletal system development disrupted, abnormal
Phenotype Annotation (1994-2006)
Fig. for (to216z)
slc35b2
to216z/to216z
nervous system quality, abnormal
pharyngeal arch 3-7 skeleton quality, abnormal
retinal ganglion cell axon guidance quality, abnormal
whole organism lethal (sensu genetics), abnormal
Karlstrom
et al.
, 1996
Table 1
slc35b2
to216z/to216z
optic tract structure, abnormal
retinal ganglion cell axon guidance process quality, abnormal
retinal ganglion cell axon misrouted, abnormal
Schilling
et al.
, 1996
Fig. Table 3
slc35b2
to216z/to216z
mandibular arch skeleton decreased length, abnormal
mandibular arch skeleton increased thickness, abnormal
pectoral fin absent, abnormal
pharyngeal arch 2 skeleton decreased length, abnormal
pharyngeal arch 2 skeleton increased thickness, abnormal
pharyngeal arch 3-7 skeleton decreased length, abnormal
pharyngeal arch 3-7 skeleton increased thickness, abnormal
Fig. Table 4
slc35b2
to216z/to216z
mandibular arch skeleton decreased size, abnormal
pharyngeal arch 2 skeleton decreased size, abnormal
pharyngeal arch 3-7 skeleton decreased size, abnormal
Trowe
et al.
, 1996
Fig. 4
slc35b2
to216z/to216z
dorsomedial optic tract composition, abnormal
retinal ganglion cell axon branched, abnormal
retinal ganglion cell axon displaced, abnormal
retinal ganglion cell axon guidance process quality, abnormal
retinal ganglion cell axon organization quality, abnormal
Table 1
slc35b2
to216z/to216z
pharyngeal arch 3-7 skeleton increased size, abnormal
telencephalon anterior-most region truncated, abnormal
telencephalon decreased size, abnormal
whole organism viability, abnormal
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