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Phenotype Figure Summary
Marker:
dpysl2b
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Guo
et al.
, 2022
Fig. 1
RW + MO3-dpysl2b
anterior commissure axon ab1-tuba labeling spatial pattern, abnormal
anterior commissure axon decreased distribution, abnormal
postoptic commissure axon ab1-tuba labeling spatial pattern, abnormal
postoptic commissure axon decreased distribution, abnormal
Fig. 2
RW + MO3-dpysl2b
anterior commissure axon ab1-tuba labeling spatial pattern, abnormal
anterior commissure axon decreased distribution, abnormal
postoptic commissure axon ab1-tuba labeling spatial pattern, abnormal
postoptic commissure axon decreased distribution, abnormal
Fig. 3
dpysl2b
wa21/wa21
(RW)
anterior commissure axon ab1-tuba labeling spatial pattern, abnormal
anterior commissure axon decreased distribution, abnormal
postoptic commissure axon ab1-tuba labeling spatial pattern, abnormal
postoptic commissure axon decreased distribution, abnormal
Fig. 5
RW + MO3-dpysl2b
, 
dpysl2b
wa21/wa21
(RW)
anterior commissure axon ab1-tuba labeling spatial pattern, abnormal
anterior commissure axon decreased distribution, abnormal
postoptic commissure axon ab1-tuba labeling spatial pattern, abnormal
postoptic commissure axon decreased distribution, abnormal
Fig. 6
RW + MO3-dpysl2b
anterior commissure axon ab1-tuba labeling spatial pattern, abnormal
anterior commissure axon decreased distribution, abnormal
postoptic commissure axon ab1-tuba labeling spatial pattern, abnormal
postoptic commissure axon decreased distribution, abnormal
Suzuki
et al.
, 2022
Fig. 2
RW + MO3-dpysl2b
CaP motoneuron mislocalised, abnormal
Carretero-Rodriguez
et al.
, 2021
Fig. 10
AB + MO1-dpysl2b
optomotor response decreased process quality, abnormal
Fig. 6
AB + MO1-dpysl2b
cranial nerve III axon defasciculated, abnormal
cranial nerve III axon increased branchiness, abnormal
cranial nerve III oculomotor nerve development decreased process quality, abnormal
Fiallos-Oliveros
et al.
, 2020
Fig. 2
dpysl2b
wa21/wa21
; rw0Tg
branchiomotor neuron neuron migration disrupted, abnormal
rhombomere 6 branchiomotor neuron displaced to rhombomere 4, abnormal
rhombomere 6 branchiomotor neuron displaced to rhombomere 5, abnormal
Fig. 3
rw0Tg + MO3-dpysl2b
, 
rw0Tg + MO1-dpysl2b
branchiomotor neuron neuron migration disrupted, abnormal
rhombomere 6 branchiomotor neuron displaced to rhombomere 4, abnormal
rhombomere 6 branchiomotor neuron displaced to rhombomere 5, abnormal
Liu
et al.
, 2018
Fig. 2
WT + MO3-dpysl2b
retinal neural layer axon decreased branchiness, abnormal
retinal neural layer axon truncated, abnormal
Tanaka
et al.
, 2012
Fig. 1
WT + MO3-dpysl2b
Rohon-Beard neuron displaced to spinal cord axis, abnormal
Bräutigam
et al.
, 2011
Fig. 5
WT + MO2-dpysl2b
central nervous system development disrupted, abnormal
central nervous system has fewer parts of type white matter, abnormal
central nervous system projection neuron axonogenesis disrupted, abnormal
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