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Phenotype Figure Summary
Marker:
cds2
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Stratman
et al.
, 2020
Fig. 1
cds2
y54/y54
; y1Tg
intersegmental vessel decreased length, abnormal
intersegmental vessel shortened, abnormal
intersegmental vessel sprouting angiogenesis decreased occurrence, abnormal
Fig. S1
y1Tg + MO2-cds2
, 
cds2
y54/y54
; y1Tg
central artery decreased amount, abnormal
hindbrain sprouting angiogenesis decreased occurrence, abnormal
intersegmental vessel decreased length, abnormal
intersegmental vessel shortened, abnormal
sprouting angiogenesis decreased occurrence, abnormal
subintestinal venous plexus absent, abnormal
subintestinal venous plexus sprouting angiogenesis decreased occurrence, abnormal
Fig. S5
cds2
y54/y54
; y1Tg
trunk vasculature malformed, abnormal
Fig. S8
y1Tg + MO2-cds2
trunk ab9-mapk labeling decreased amount, abnormal
Zhao
et al.
, 2019
Fig. 1
y1Tg + MO2-cds2
, 
cds2
cas008/cas008
; y1Tg
intersegmental vessel decreased size, abnormal
intersegmental vessel malformed, abnormal
trunk vasculature malformed, abnormal
whole organism
vegfaa
expression increased amount, abnormal
Fig. 3
cds2
cas008/cas008
; y1Tg
intersegmental vessel malformed, abnormal
trunk vasculature malformed, abnormal
Fig. 4
cds2
cas008/cas008
; y1Tg
intersegmental vessel malformed, abnormal
trunk vasculature malformed, abnormal
Fig. 6
cds2
cas008/cas008
; y1Tg
intersegmental vessel malformed, abnormal
trunk vasculature malformed, abnormal
Fig. 7
y1Tg + MO2-cds2
whole organism 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate decreased amount, abnormal
Fig. S1
cds2
cas008/cas008
; y1Tg
whole organism
egln3
expression increased amount, abnormal
whole organism
epoa
expression increased amount, abnormal
whole organism
igfbp1a
expression increased amount, abnormal
Hill
et al.
, 2013
Fig. 6
cds2
zy14/zy14
; s843Tg
cranial vasculature absent, abnormal
intersegmental vessel absent, abnormal
Pan
et al.
, 2012
Fig. 1
cds2
y54/y54
; y1Tg
angiogenesis disrupted, abnormal
central artery decreased length, abnormal
intersegmental vessel decreased length, abnormal
Fig. 2
y1Tg + MO2-cds2
, 
cds2
y54/y54
; y1Tg
angiogenesis disrupted, abnormal
intersegmental vessel decreased length, abnormal
Fig. 3
y1Tg + MO2-cds2
angiogenesis disrupted, abnormal
blood vessel endothelial cell decreased amount, abnormal
intersegmental vessel decreased length, abnormal
positive regulation of ERK1 and ERK2 cascade decreased magnitude, abnormal
positive regulation of vascular endothelial growth factor signaling pathway decreased occurrence, abnormal
Fig. 4
y1Tg + MO2-cds2
angiogenesis disrupted, abnormal
intersegmental vessel decreased length, abnormal
positive regulation of ERK1 and ERK2 cascade decreased magnitude, abnormal
positive regulation of vascular endothelial growth factor signaling pathway decreased occurrence, abnormal
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