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Phenotype Figure Summary
Marker:
lmna
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Elfatih
et al.
, 2022
Figure 4
WT + MO6-lmna
heart contraction decreased rate of continuous process, abnormal
heart contraction increased rate of continuous process, abnormal
Figure 5
sd2Tg; zf3671Tg + MO6-lmna
atrioventricular valve morphology, abnormal
atrium shape, abnormal
cardiac ventricle shape, abnormal
Nicolas
et al.
, 2021
Fig. 1
lmna
ot300/ot300
whole organism
lmna
expression decreased amount, abnormal
whole organism
lmnb1
expression decreased amount, abnormal
Fig. 2
lmna
ot300/ot300
cardiac ventricle decreased functionality, abnormal
Fig. 3
lmna
ot300/ot300
, 
lmna
ot300/+
somite slow muscle cell damaged, abnormal
swimming behavior process quality, abnormal
Fig. 4
lmna
ot300/ot300
whole organism
jun
expression decreased amount, abnormal
whole organism
nfkb2
expression decreased amount, abnormal
whole organism ab7-mapk labeling increased amount, abnormal
Hayashi
et al.
, 2020
Fig. 3
lmna
bw25/bw25
atrioventricular canal cardiac conduction decreased process quality, abnormal
cardiac ventricle cardiac conduction decreased process quality, abnormal
heart contraction decreased rate, abnormal
heart decreased functionality, abnormal
Fig. S5
lmna
bw25/bw25
cardiac muscle cell nucleus morphology, abnormal
Fig. S6
WT + CRISPR3-lmna + CRISPR4-lmna + CRISPR5-lmna + CRISPR6-lmna
cardiac ventricle cardiac conduction decreased process quality, abnormal
heart contraction decreased rate, abnormal
Koshimizu
et al.
, 2011
Fig. 2
WT + MO3-lmna
integument rough, abnormal
Fig. 4
WT + MO3-lmna
, 
WT + MO5-lmna
ceratohyal cartilage mislocalised posteriorly, abnormal
Meckel's cartilage alignment palatoquadrate cartilage, abnormal
myotome slow muscle cell decreased amount, abnormal
myotome slow muscle cell undulate, abnormal
pharyngeal arch cartilage physical object quality, abnormal
Fig. 5
WT + MO3-lmna
, 
WT + MO5-lmna
brain apoptotic, abnormal
cellular senescence increased occurrence, abnormal
mitotic M phase duration, abnormal
mitotic S phase duration, abnormal
trunk apoptotic, abnormal
Fig. S6
WT + MO3-lmna
, 
WT + MO5-lmna
fat cell decreased amount, abnormal
fat cell differentiation decreased occurrence, abnormal
Vogel
et al.
, 2009
Fig. 2
WT + MO1-lmna
blood circulation disrupted, abnormal
heart decreased contractility, abnormal
pericardium edematous, abnormal
sinus venosus increased accumulation blood, abnormal
Fig. 4
WT + MO1-lmna
heart contraction decreased rate, abnormal
regulation of heart rate disrupted, abnormal
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