Genomic Feature
m582
- ID
- ZDB-ALT-980203-584
- Name
- m582
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Driever Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 23: 2790222 (GRCz11) (1) Details
- Nucleotide change
- G/T
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- G>T (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Gly>Stop at position 11 (1)
- Flanking Sequence
-
ATTAATAAAGCAGAATCTGTGATTTTTTTTCTCTCTCTCGTTGTTTGCTCATCAAAATAAAGCGTTGTTGGTCATATCGAAGCAAATCACGCATCATAAGTCAGATCAACTCAATTTAATCTACTTAAACATACTAGAATTGAATGATTAGCTTTGATTAAGATCTGCTGTTCTTGTGTGTGATATAATAATATTAATAATCCGTTATGCTCTCATAATCAATACATTAATCACAGCTAATGACTGTGTATTTTTAAATATATAAGTATAAATTAGCATATAGGTGAAGTGTGAATGTACACATGTGGATGTATTGTACAGCAGGCCTCTCTCTATGTGTGTGTGTGTGTGTGTGTGTGTGTGAGCTCTCCTTTATGCCTTACATTTGCTTTATGTGGTGTTTCTGATGCTTGTTTTTGCTAGGTGTCCTGTGAGCGTTTCTGAGAGGAACTGAAGAACAAACAGGGGAAATGGCTGCGAGCGCGGGCTTCTCCTCCAAT
G/T GACCTGTACCCTGGGCTCTGAGCGACACCGAGGTGAACAATCTGTACCGGGATCTGGAGCTGGGCACCGTACTCACGCTCTATTACTCCAAAAAGTCCCAGAGACCCGAGAGGAGGACGTTTCAAGTCAAGCTCGAGACCAGGCAGATTATCTGGACCAGAGGAACGGATAAAATCGAGGGCGAAAGTAAGTTCCCGATGCTAATCGCTGCGGGTTTGGATTCAGAAACCAACAGTTTTTTTTAAAAAGCCCCAAAGTGTGTGTCAGTTTTCTGGGGCTCGTTTTTGTTGTGTTGTCCATGACTGGAGCTGTTAGAACCAAAACATACAAAACATGCCCTCCTCCTCCTCCTCTTCTCTTTCTTTACTCCCGGGCAGGGCCAGACTGAGTCTGCACTGTAGAAGTGCTGGGCTCCACACAATCAATTTGTGTTGGGACGACGTAAAGGAATTAACTTAACTCATTAGTTTTCACTAATTTAAGTTGATCGAACATAAAAC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| plcg1m582/m582 | Homozygous | Unknown | Fig. 4 from Lausser et al., 2018 | ||
| plcg1m582/m582 (AB) | Homozygous | Unknown | 4 figures  from 3 publications | Fig. 2 from Rottbauer et al., 2005 |
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Supplemental Information
- Genotyping protocol
- None
- Lausser, L., Siegle, L., Rottbauer, W., Frank, D., Just, S., Kestler, H.A. (2018) Semantic Multi-Classifier Systems Identify Predictive Processes in Heart Failure Models across Species. Biomolecules. 8(4):
- Rottbauer, W., Just, S., Wessels, G., Trano, N., Most, P., Katus, H.A., and Fishman, M.C. (2005) VEGF-PLC{gamma}1 pathway controls cardiac contractility in the embryonic heart. Genes & Development. 19(13):1624-1634
- Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C. (1996) A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123:37-46
- Stainier, D.Y., Fouquet, B., Chen, J.N., Warren, K.S., Weinstein, B.M., Meiler, S.E., Mohideen, M.A., Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Driever, W., and Fishman, M.C. (1996) Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123:285-292
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