Genomic Feature
rk3
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 7: 53116984 (GRCz11) (1) Details
- Nucleotide change
- A/T
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- T>A in Intron 1 (1)
- Transcript Consequence
- Splice Site, Premature Stop (1)
- Protein Consequence
- None
- Flanking Sequence
-
TTACACCCGAGATTGCATACTTACACAGTAACATTAAACAGCAACGTATGTGGCAAAAAGTAATAAATCTAAATTAAAACCGTAGGCAGACAACATTAGGATGCCAACACAACCAATAAATTATAGTTCATACAGACACAGTTTAGAAGGTACTTTTTAGTGGCAGCAGCAAATTAAAGTACAAGTACGTACTTGGTATGCAGTTTAAAACAGTCATGGCATTTGGCGGAAACTGGAGTGAAAACTAACTAACGCAAATATTAGCATTCTCGAAAATCGATATCAAACACCTCCTGTCCTCTAGAAAGATTTAACTGTTAAGGTAATTTAACACATTTGCTTCAGCATTTTACAGAGATTACCGAAAACAACCTAACTTACCTTTGCCTAGTCTTTTGCCACTGTGAAGGTGATTTCGGTGTACTTTAAAAACAAATTCCTCCAACTCAAACCCAGGTGTACATATCGACATATGCGTATATCCACTCGAAAAGACCTAC
A/T ACAAATAAAAACGGTTTAAAACAAACCAAAACCTTCATTGTCCTCGACGAGTTTCGGTCAAGAGCTCGACGCCATTGAGAAGAAAAAAAGTCTTACCTGAAAAAGAAAAAAGATAACTCCTAATCCCACAGTTGTTACACAAGCCATTTGACTCGCTACAAGTCAAATCCTTTAGCGTTTTAATCCCTCGAGTGTGTTAAATAAATCGCAGCTCTTCCTTCCAACGTCCTCTCAGCCGCGAAATTGAGGAAATGGTCTTCAGCAGGTAGAGAGAGTCTTAGGAACTGACGAAACCAGGTGACCTCGCCCATCCGGTAATCACAGTTTCCAAATATGGGTATGCTCGTTCGTTTAGACACTCCTATAAAACACAGGTACCCTAATCAGTGAACTACGTGTAAAAATTGGAAACATTAAATGTCACTTCTGTTCAAGATTTGATTTGCTCATCTATCTAAAATAAAAGACTGTCAAACGTTTATAGCTACCTTAAAGAGTGA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cdh1rk3/rk3 | Homozygous | ♀+/- ♂+/- | 2 figures  from Shimizu et al., 2005 | 2 figures from Shimizu et al., 2005 | |
| cdh1rk3/rk3 | Homozygous | ♀-/- ♂-/- | Fig. 4 from Shimizu et al., 2005 | Fig. 4 from Shimizu et al., 2005 | |
| cdh1rk3/rk3 (AB) | Homozygous | Unknown | |||
| cdh1rk3/rk3; kca66Tg; kca6Tg; oki011Tg | Complex | 4 figures from Mochizuki et al., 2017 | 2 figures from Mochizuki et al., 2017 |
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Supplemental Information
- Genotyping protocol
- None
- Mochizuki, T., Luo, Y.J., Tsai, H.F., Hagiwara, A., Masai, I. (2017) Cell division and cadherin-mediated adhesion regulate lens epithelial cell movement in zebrafish. Development (Cambridge, England). 144:708-719
- Mochizuki, T., Suzuki, S., Masai, I. (2014) Spatial pattern of cell geometry and cell-division orientation in zebrafish lens epithelium. Biology Open. 3(10):982-94
- Shimizu, T., Yabe, T., Muraoka, O., Yonemura, S., Aramaki, S., Hatta, K., Bae, Y.K., Nojima, H., and Hibi, M. (2005) E-cadherin is required for gastrulation cell movements in zebrafish. Mechanisms of Development. 122(6):747-763
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