Genomic Feature
hi1688Tg
- ID
- ZDB-ALT-020426-6
- Name
- hi1688Tg
- Synonyms
-
- hi1688 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the plus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 14: 31102554 - 31102555 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Exon 4 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| gpc4hi1688Tg/hi1688Tg | Homozygous | ♀+/- ♂+/- | 6 figures  from 4 publications | 2 figures from 2 publications | |
| gpc4hi1688Tg/+ (AB) | Heterozygous | Unknown | |||
| gpc4hi1688Tg | Unknown | Unknown | Fig. for (hi1688) from Phenotype Annotation (1994-2006) | ||
| gpc4hi1688Tg/hi1688Tg; ir937Tg | Complex | 3 figures from Ling et al., 2017 | |||
| wlszf759/zf759; gpc4hi1688Tg/hi1688Tg | Complex | Fig. 4 from Rochard et al., 2016 |
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Supplemental Information
- Genotyping protocol
- hi1688tg.pdf
- Ling, I.T., Rochard, L., Liao, E.C. (2017) Distinct requirements of wls, wnt9a, wnt5b and gpc4 in regulating chondrocyte maturation and timing of endochondral ossification. Developmental Biology. 421(2):219-232
- Miles, L.B., Mizoguchi, T., Kikuchi, Y., Verkade, H. (2017) A role for planar cell polarity during early endoderm morphogenesis. Biology Open. 6:531-539
- Rochard, L., Monica, S.D., Ling, I.T., Kong, Y., Roberson, S., Harland, R., Halpern, M., Liao, E.C. (2016) Roles of Wnt pathway genes wls, wnt9a, wnt5b, frzb and gpc4 in regulating convergent-extension during zebrafish palate morphogenesis. Development (Cambridge, England). 143:2541-7
- Harrington, M.J., Hong, E., Fasanmi, O., and Brewster, R. (2007) Cadherin-mediated adhesion regulates posterior body formation. BMC Developmental Biology. 7(1):130
- Nissen, R.M., Amsterdam, A., and Hopkins, N. (2006) A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for Endothelin-1 expression. BMC Developmental Biology. 6:28
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
- Golling, G., Amsterdam, A., Sun, Z., Antonelli, M., Maldonado, E., Chen, W., Burgess, S., Haldi, M., Artzt, K., Farrington, S., Lin, S.Y., Nissen, R.M., and Hopkins, N. (2002) Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nature Genetics. 31(2):135-140
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