| ZFIN ID: ZDB-EXP-250103-8 |
Experiment Conditions Description: chemical treatment by environment: doxycycline, chemical treatment by environment: 2-deoxy-D-glucose
| chemical treatment by environment: doxycycline |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | doxycycline |
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| Synonyms: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 5-hydroxy-alpha-6-deoxytetracycline, 6alpha-deoxy-5-oxytetracycline, doxiciclina, Doxycyclin, Doxycycline, doxycycline (anhydrous), doxycyclinum, Jenacyclin, Supracyclin, Vibramycin |
| Definition: | Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. |
| Ontology: | ChEBI [CHEBI:50845] ( EBI ) |
| chemical treatment by environment: 2-deoxy-D-glucose |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 2-deoxy-D-glucose |
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| Synonyms: | 2-deoxy-D-arabino-hexose, 2-Deoxy-D-glucose, 2-Deoxy-D-mannose, D-2dGlc, D-arabino-2-Deoxyhexose, Deoxyglucose |
| Definition: | A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent. |
| Ontology: | ChEBI [CHEBI:15866] ( EBI ) |
| Publication: | Fei et al., 2020 |
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