| ZFIN ID: ZDB-EXP-240607-1 |
Experiment Conditions Description: chemical treatment by environment: sulfopin
| chemical treatment by environment: sulfopin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | sulfopin |
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| Synonyms: | 2-chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-neopentylacetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda(6)-thiolan-3-yl)acetamide, PIN1-3 |
| Definition: | A sulfone that is thiolane substituted by two oxo groups at position 1 and by a (chloroacetyl)(2,2-dimethylpropyl)amino group at position 3. It is a covalent inhibitor of Pin1 (Ki = 17 nM) that inhibits Myc-driven tumors in vivo. |
| Ontology: | ChEBI [CHEBI:231413] ( EBI ) |
| Publication: | Dubiella et al., 2021 |
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