| ZFIN ID: ZDB-EXP-240528-4 |
Experiment Conditions Description: light ablation: axon: Mauthner neuron, chemical treatment by environment: tunicamycin
| light ablation: axon: Mauthner neuron |
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| Name: | light ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses focused light to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000170] |
| Name: | axon |
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| Synonyms: | |
| Definition: | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. |
| Ontology: | GO: Cellular Component [GO:0030424] QuickGO AmiGO |
| Name: | Mauthner neuron |
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| Synonyms: | |
| Definition: | Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon. |
| Ontology: | Anatomy Ontology [ZFA:0009149] |
| chemical treatment by environment: tunicamycin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | tunicamycin |
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| Synonyms: | Tunicamycin |
| Definition: | A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety. |
| Ontology: | ChEBI [CHEBI:29699] ( EBI ) |
| Publication: | Wang et al., 2022 |
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