| ZFIN ID: ZDB-EXP-240409-1 |
Experiment Conditions Description: transection: spinal cord, chemical treatment by environment: Ac-Tyr-Val-Ala-Asp-chloromethylketone
| transection: spinal cord |
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| Name: | transection |
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| Synonyms: | |
| Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
| Name: | spinal cord |
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| Synonyms: | medulla spinalis, spinal cord structure |
| Definition: | |
| Ontology: | Anatomy Ontology [ZFA:0000075] |
| chemical treatment by environment: Ac-Tyr-Val-Ala-Asp-chloromethylketone |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Ac-Tyr-Val-Ala-Asp-chloromethylketone |
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| Synonyms: | Ac-L-Tyr-L-Val-L-Ala-L-Asp-chloromethylketone, Ac-YVAD-cmk, N-acetyl-L-tyrosyl-L-valyl-N-[(2S)-1-carboxy-4-chloro-3-oxobutan-2-yl]-L-alaninamide, N-acetyl-tyrosinyl-valinyl-alanyl-aspartyl chloromethyl ketone, N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone, N-acetyltyrosinylvalinylalanylaspartylchloromethyl ketone |
| Definition: | A tetrapeptide composed of L-tyrosine, L-valine, L-alanine, and L-aspartic acid joined in sequence by peptide linkages and in which the amino terminus in substituted by an acetyl group and the carboxy terminus is substituted by a chloromethyl group. |
| Ontology: | ChEBI [CHEBI:230455] ( EBI ) |
| Publication: | Keatinge et al., 2021 |
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