| ZFIN ID: ZDB-EXP-240318-4 |
Experiment Conditions Description: chemical treatment by environment: Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish), chemical treatment by environment: SR11302
| chemical treatment by environment: Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish) |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish) |
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| Synonyms: | TNF-a, TNFalpha |
| Definition: | Tumor necrosis factor alpha is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. Protein Sequence:AAIHLTGGYN SESKTLDWRD DQDQAFSSGG LKLVNREIII PDDGIYFVYS QVSLHISCTS ELTEEQVLMS HAVMRFSESY GGKKPLFSAI RSICTQEPES ENLWYNTIYL GAAFHLREGD RLGTDTTTAL LPMVENDNGK TFFGVFGL |
| Ontology: | ChEBI [CHEBI:197439] ( EBI ) |
| chemical treatment by environment: SR11302 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | SR11302 |
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| Synonyms: | (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid, (2E,4E,6Z,8E)-3-methyl-7-(p-tolyl)-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid, (E,E,Z,E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, SR 11302, SR-11303 |
| Definition: | A retinoid that is all-trans-retinoic acid in which the methyl group at position 9 is replaced by a 4-methylphenyl group. It is an inhibitor of activator protein-1 which exhibits antitumour effects in vivo. |
| Ontology: | ChEBI [CHEBI:197438] ( EBI ) |
| Publication: | Cavone et al., 2021 |
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