| ZFIN ID: ZDB-EXP-230222-13 |
Experiment Conditions Description: heat shock, chemical treatment by environment: dactolisib
| heat shock |
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| Name: | heat shock |
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| Synonyms: | |
| Definition: | Temperature shock condition in which fish are subjected for a short period of time to temperature higher than the controlled temperature. The standard controlled temperature (according to the zebrafish book) is 28.5 degrees C. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000166] |
| chemical treatment by environment: dactolisib |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | dactolisib |
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| Synonyms: | 2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile, BEZ 235, BEZ-235, BEZ235, NVP BEZ235, NVP-BEZ 235, NVP-BEZ235, NVPBEZ235 |
| Definition: | An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment. |
| Ontology: | ChEBI [CHEBI:71952] ( EBI ) |
| Publication: | Xu et al., 2019 |
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