ZFIN ID: ZDB-EXP-220602-2
Experiment Conditions Description: chemical treatment: SIS3
chemical treatment: SIS3
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: SIS3
Synonyms: (2E)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one hydrochloride, (E)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one HCl, specific inhibitor of SMAD3
Definition: A hydrochloride resulting from the reaction of SIS3 free base with 1 mol eq. of hydrogen chloride.
Ontology: ChEBI [CHEBI:87461]  ( EBI )
Publication: Boezio et al., 2020