| ZFIN ID: ZDB-EXP-210819-9 |
Experiment Conditions Description: resection: lateral rectus, chemical treatment by environment: SU5402
| resection: lateral rectus |
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| Name: | resection |
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| Synonyms: | |
| Definition: | Surgical manipulation in which a particular organ, appendage, or part of an organism is removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000171] |
| Name: | lateral rectus |
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| Synonyms: | lateral recti, posterior rectus |
| Definition: | Extraocular muscle that runs parallel to the long axis of the fish and inserts on the caudal side of the eye at the sclera-corneal . The lateral rectus muscles originate substantially posterior to the other rectus muscles. The lateral rectus is innervated by the abducens nerve. The unsegmented paraxial head mesoderm contributes to the lateral rectus. |
| Ontology: | Anatomy Ontology [ZFA:0000383] |
| chemical treatment by environment: SU5402 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | SU5402 |
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| Synonyms: | 3-[3-(2-carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone, 3-{4-methyl-2-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, 3-{[3-(2-carboxyethyl)-4-methylpyrrol-2-yl]methylene}-2-indolinone, SU 5402, SU-5402 |
| Definition: | An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. |
| Ontology: | ChEBI [CHEBI:63449] ( EBI ) |
| Publication: | Zhao et al., 2020 |
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