ZFIN ID: ZDB-EXP-210818-9
Experiment Conditions Description: chemical treatment by injection: lipopolysaccharide, chemical treatment by environment: dexamethasone, chemical treatment by environment: cortisol
chemical treatment by injection: lipopolysaccharide
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: lipopolysaccharide
Synonyms: Lipopolysaccharide, lipopolysaccharides, LPS
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Ontology: ChEBI [CHEBI:16412]  ( EBI )
chemical treatment by environment: dexamethasone
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: dexamethasone
Synonyms: (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone, 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, 9alpha-fluoro-16alpha-methylprednisolone, Aeroseb-Dex, Auxiron, Azium, Calonat, Corson, Cortisumman, Decacort, Decadron, Decaject, Decalix, Decameth, Dexacortal, Dexacortin, dexametasona, dexamethasone, dexamethasonum, Dexason, Dexasone, DexPak, Diodex, fluormethylprednisolone, Hexadrol, Maxidex, Millicorten, Oradexon, Ozurdex, Solurex, Zema-Pak
Definition: A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Ontology: ChEBI [CHEBI:41879]  ( EBI )
chemical treatment by environment: cortisol
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: cortisol
Synonyms: (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione, 11beta-hydrocortisone, 17-hydroxycorticosterone, 4-pregnen-11beta,17alpha,21-triol-3,20-dione, cortisol, hidrocortisona, hydrocortisone, hydrocortisonum, Kendall's compound F, Reichstein's substance M
Definition: A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses.
Ontology: ChEBI [CHEBI:17650]  ( EBI )
Publication: Hsu et al., 2018