ZFIN ID: ZDB-EXP-210125-6
Experiment Conditions Description: chemical treatment: DAPT, chemical treatment: N-phenylthiourea
chemical treatment: DAPT
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: DAPT
Synonyms: gamma-secretase inhibitor IX, GSI-IX, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
Definition: A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a gamma-secretase inhibitor.
Ontology: ChEBI [CHEBI:86193]  ( EBI )
chemical treatment: N-phenylthiourea
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: N-phenylthiourea
Synonyms: 1-phenyl-2-thiourea, 1-phenylthiourea, alpha-phenylthiourea, monophenyl thiourea, phenyl-2-thiourea, phenylthiocarbamide, phenylthiourea, PhNHC(=S)NH2, PhNHC(S)NH2, PhNHCSNH2, PTC, PTU
Definition: A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in N-phenylthiourea being used in paternity testing prior to the advent of DNA testing.
Ontology: ChEBI [CHEBI:46261]  ( EBI )
Publication: Hsu et al., 2019