| ZFIN ID: ZDB-EXP-210115-5 |
Experiment Conditions Description: chemical treatment by environment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
| chemical treatment by environment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide |
|---|---|
| Synonyms: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, 4-dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide, D237, histone deacetylase inhibitor III, M-344, M344, N-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide |
| Definition: | A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines. |
| Ontology: | ChEBI [CHEBI:125562] ( EBI ) |
| Publication: | Asad et al., 2019 |
|---|