| ZFIN ID: ZDB-EXP-201006-5 |
Experiment Conditions Description: chemical treatment: clotrimazole, chemical treatment: lonafarnib
| chemical treatment: clotrimazole |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | clotrimazole |
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| Synonyms: | 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole, 1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole, 1-(o-Chloro-alpha,alpha-diphenylbenzyl)imidazole, 1-(o-Chlorotrityl)imidazole, 1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole, Clotrimazole, Lotrimin (TN), Mycelex (TN) |
| Definition: | A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group. |
| Ontology: | ChEBI [CHEBI:3764] ( EBI ) |
| chemical treatment: lonafarnib |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | lonafarnib |
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| Synonyms: | 4-(2-{4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidin-1-yl}-2-oxoethyl)piperidine-1-carboxamide, lonafarnib, lonafarnibum, SCH 66336 |
| Definition: | A 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor. |
| Ontology: | ChEBI [CHEBI:47097] ( EBI ) |
| Publication: | Precazzini et al., 2019 |
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