| ZFIN ID: ZDB-EXP-200910-22 |
Experiment Conditions Description: chemical treatment: okadaic acid, chemical treatment: U0126
| chemical treatment: okadaic acid |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | okadaic acid |
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| Synonyms: | (2R)-2-hydroxy-3-{(2S,5R,6R,8S)-5-hydroxy-8-[(2R,3E)-4-((2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl)but-3-e, 9,10-Deepithio-9,10-didehydroacanthifolicin, Okadaic acid |
| Definition: | A polycyclic ether that is produced by several species of dinoflagellates, and is known to accumulate in both marine sponges and shellfish. A polyketide, polyether derivative of a C38 fatty acid, it is one of the primary causes of diarrhetic shellfish poisoning (DSP). It is a potent inhibitor of specific protein phosphatases and is known to have a variety of negative effects on cells. |
| Ontology: | ChEBI [CHEBI:44658] ( EBI ) |
| chemical treatment: U0126 |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | U0126 |
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| Synonyms: | (2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylene}succinonitrile, FT-1069-1, U 0126, U-0126, U0126 |
| Definition: | An aryl sulfide that is (2Z,3Z)-bis[amino(sulfanyl)methylidene]butanedinitrile in which the sulfanyl hydrogens are replaced by 2-aminophenyl groups. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties. |
| Ontology: | ChEBI [CHEBI:90693] ( EBI ) |
| Publication: | Xin et al., 2019 |
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