| ZFIN ID: ZDB-EXP-190726-4 |
Experiment Conditions Description: light ablation: pronephros, chemical treatment by environment: 3PO
| light ablation: pronephros |
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| Name: | light ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses focused light to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000170] |
| Name: | pronephros |
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| Synonyms: | embryonic kidney, pronephric nephron |
| Definition: | The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion. |
| Ontology: | Anatomy Ontology [ZFA:0000151] |
| chemical treatment by environment: 3PO |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 3PO |
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| Synonyms: | (2E)-3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, (2E)-3-(pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3PO |
| Definition: | A member of the class of pyridines that is pyridine substituted by a 3-oxo-3-(pyridin-4-yl)prop-1-en-1-yl group at position 3. An inhibitor of PFKFB3 kinase, an enzyme with a key role in glycolysis. |
| Ontology: | ChEBI [CHEBI:144367] ( EBI ) |
| Publication: | Yakulov et al., 2018 |
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