| ZFIN ID: ZDB-EXP-190708-8 |
Experiment Conditions Description: chemical treatment by environment: 17alpha-estradiol, chemical treatment by environment: fulvestrant
| chemical treatment by environment: 17alpha-estradiol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 17alpha-estradiol |
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| Synonyms: | (17alpha)-estra-1,3,5(10)-triene-3,17-diol, 1,3,5-estratriene-3,17alpha-diol, 13beta-methyl-1,3,5(10)-gonatriene-3,17alpha-diol, 17-epiestradiol, 17alpha-Estradiol, 17alpha-oestradiol, 3,17alpha-dihydroxyestra-1,3,5(10)-triene, 3,17alpha-dihydroxyoestra-1,3,5(10)-triene, alfatradiol, alfatradiolum, alpha-estradiol, epiestradiol, epiestrol, estra-1,3,5(10)-triene-3,17alpha-diol, estra-1,3,5(10)trien-3,17alpha-diol, Estradiol-17alpha, oestra-1,3,5(10)-triene-3,17alpha-diol |
| Definition: | An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer). |
| Ontology: | ChEBI [CHEBI:17160] ( EBI ) |
| chemical treatment by environment: fulvestrant |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | fulvestrant |
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| Synonyms: | (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol, Faslodex, fulvestrant, fulvestrantum, ICI 182780, ICI-182780 |
| Definition: | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. |
| Ontology: | ChEBI [CHEBI:31638] ( EBI ) |
| Publication: | Carroll et al., 2014 |
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