| ZFIN ID: ZDB-EXP-181228-2 |
Experiment Conditions Description: chemical treatment by environment: ouabain, chemical treatment by environment: afimoxifene
| chemical treatment by environment: ouabain |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | ouabain |
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| Synonyms: | 3-(6-deoxy-alpha-L-mannopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide, 3-(alpha-L-rhamnopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide, G-Strophanthin, Ouabagenin L-Rhamnoside, Ouabagenin-L-rhamnosid, Ouabain, Ouabain anhydrous, Ouabaine, Oubain, Strodival |
| Definition: | A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus. |
| Ontology: | ChEBI [CHEBI:472805] ( EBI ) |
| chemical treatment by environment: afimoxifene |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | afimoxifene |
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| Synonyms: | 4-hydroxytamoxifen, 4-monohydroxytamoxifen, 4-OHT, afimoxifene |
| Definition: | A tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen. |
| Ontology: | ChEBI [CHEBI:44616] ( EBI ) |
| Publication: | Dasgupta et al., 2018 |
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