| ZFIN ID: ZDB-EXP-181227-6 |
Experiment Conditions Description: hypoxia, chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F
| hypoxia |
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| Name: | hypoxia |
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| Synonyms: | |
| Definition: | An oxygen content with low concentration of oxygen. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000189] |
| chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Z-Val-Ala-Asp(OMe)-CH2F |
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| Synonyms: | N-[(benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide, pan-caspase inhibitor, Z-L-Val-L-Ala-L-Asp(OMe)-CH2F, Z-VAD(OMe)-FMK, Z-VAD-FMK, Z-Val-Ala-Asp(OMe)-fluoromethyl ketone, Z-Val-Ala-Asp(OMe)-FMK |
| Definition: | A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor. |
| Ontology: | ChEBI [CHEBI:137045] ( EBI ) |
| Publication: | Kamei et al., 2018 |
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