ZFIN ID: ZDB-EXP-181227-5
Experiment Conditions Description: oxygen content, hypoxia, chemical treatment by environment: leflunomide
oxygen content
Name: oxygen content
Synonyms:
Definition: A gas composition condition that alters the concentraion of oxygen.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000187]
hypoxia
Name: hypoxia
Synonyms:
Definition: An oxygen content with low concentration of oxygen.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000189]
chemical treatment by environment: leflunomide
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: leflunomide
Synonyms: 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide, 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide, 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide, alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide, Arava, leflunomida, leflunomide, leflunomidum
Definition: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Ontology: ChEBI [CHEBI:6402]  ( EBI )
Publication: Kamei et al., 2018